Description
Chromomycin A3 is produced by the strain of Streptomyces olivochromogenes 69895. The major component of the chromomycin complex of the aureolic acid class; isolated from several streptomyces species; exhibits a broad biological profile as an antibacterial, antifungal and antitumour agent; binds reversibly to GC-specific DNA ligand in the minor groove which inhibits transcription, DNA gyrase and topoisomerase II activity